Prerequisite: Graduate Student or permission of instructor (3 credits) This course is intended to examine the process by which a first layout is developed for a new vehicle platform. The course will focus on the layout of the major space-defining vehicle subsystems required to arrive at a preliminary vehicle package drawing. The process followed will be based on systems engineering: requirements-to-design concepts -to- performance prediction -to- comparison to requirements -to- iteration.
Prerequisite: permission of department (3 credits) This capstone project course is intended to provide students with an industrially-relevant team project work experience in automotive engineering.
Prerequisite: permission of the instructor. (3 credits) Lean Program Engineering provides an opportunity to acquire and demonstrate mastery of critical lean product design engineering disciplines within the context of an automotive vehicle program team. The course identify and integrate engineering skills, tools and processes required for successful automotive vehicle project planning and completion consistent with lean product development principles.
Prerequisite: ME235 (3 credits) Introduction to the challenges of power generation for a global society using the thermodynamics to understand basic principles and technology limitations. Covers current and future demands for energy; methods of power generation including fossil fuel, solar, wind and nuclear; associated detrimental by-products; and advanced strategies to improve power densities, efficiencies and emissions
Prerequisite: Graduate Standing or permission of instructor. IIIa, III (3 credits) Automatic transmission is a key element of automotive vehicles for improved driving comfort. This course will introduce the mechanisms, design and control of modern transmission systems. The emphasis will be on the dynamic analysis, and the application of modern control theories for the overall control design, analysis and synthesis problems.
Prerequisite: Graduate Standing or permission of instructor. I, II, IIIa, III (3 credits) Selected topics pertinent to Automotive Engineering.
Prerequisite: senior standing (3 credits) Technologies and economics of electric power generation, transmission, and distribution are discussed. Centralized versus distributed generation, and fossil fuels versus renewable resources, are considered in regard to engineering, market and regulatory principles. Students develop an understanding of energy challenges confronting society and investigate technologies that seek to address future needs.
Prerequisite: ChemE 344, and Biochem 415 or equivalent; permission of instructor. II (3 credits) Concepts necessary in the adaptation of biological and biochemical principles to industrial processing in biotechnology and pharmaceutical industries. Topics include rational screening, functional genomics, cell cultivation, oxygen transfer, etc. Lectures, problems, and library study will be used.
Prerequisite: Senior or graduate standing, permission by instructor. I (3 credits) Concepts necessary in the adaptation of engineering principles to pharmaceutical and life sciences-related industries. Topics include process engineering in drug discovery, high throughput characterization and optimization of new chemical entities, solid-state engineering and intelligent pharmaceutical manufacturing systems. Lectures, problems, Internet and library study will be used to develop the ideas presented.
Prerequisite: Pharm Sci 560 or permission of instructor II Alternate Years (2 credits) This course teaches the basic concepts in population pharmacokinetic (PK) and pharmacodynamic (PD) modeling and its application in drug development. The material covers both the theoretical and practical aspects of the population approach. Software (WINNONLIN, NONMEN, and SPLUS) will be installed in a centralized area for hands-on training and learning.
Prerequisite: ChemE 344. I (3 credits) Analysis of kinetic, thermal, diffusive, and flow factors on reactor performance. Topics include batch, plug flow, backmix reactors, empirical rate expressions, residence time analysis, catalytic reactions, stability, and optimization.
ChE532/Pharm761 Population Pharmacokinetics
Prerequisite: graduate standing. (3 credits) Foundations of transport phenomena. Heat and mass transfer with chemical reaction in three dimensions, selective motion. Unsteady energy and mass balances in three dimensions. Distributions in more than one variable. Boundary layer theory. Estimation of interfacial transport coefficients. Dispersive flows: Taylor Dispersion. Application to equipment design.
Prerequisite: graduate standing. I, II (1 credit) This seminar will feature invited speakers from pharmaceutical, biomedical, and other life sciences-related industries, and academic institutions.
Prerequisite: permission of instructor. I (2 credits) Science- and technology-based rationale behind various regulatory issues involved in pharmaceutical and related industries.
Prerequisite: MATH 215 and MATH 216 and PHYSICS 240 or graduate standing (4 credits)
Micro electro mechanical systems (MEMS), devices, and technologies. Micro-machining and microfabrication techniques, including planar thin-film processing, silicon etching, wafer bonding, photolithography, deposition, and etching. Transduction mechanisms and modeling in different energy domains. Analysis of micromachined capacitive, piezoresistive, and thermal sensors/actuators and applications. Computer-aided design for MEMS layout, fabrication, and analysis.
Prerequisite: (EECS 216 or EECS 306, and EECS 401) or graduate standing I (4 credits) Digital transmission techniques in data communications, with application to computer and space communications; design and detection of digital signals for low error rate; forward and feedback transmission techniques; matched filters; modems, block and convolutional coding; Viterbi decoding.
Prerequisite: EECS 281 or graduate standing. I, II (4 credits) Pragmatic aspects of the production of software systems, dealing with structuring principles, design methodologies and informal analysis. Emphasis is given to development of large, complex software systems. A term project is usually required.
Prerequisite: EECS 414. II (4 credits) Advanced micro electro mechanical systems (MEMS) devices and technologies. Transduction techniques, including piezoelectric, electrothermal, and resonant techniques. Chemical, gas, and biological sensors, microfluidic and biomedical devices. Micromachining technologies such as laser machining and microdrilling, EDM, materials such as SiC and diamond. Sensor and actuator analysis and design through CAD.
Prerequisite: EECS 414 (4 credits) Review of interface electronics for sense and drive and their influence on device performance, interface standards, MEMS and circuit noise sources, packaging and assembly techniques, testing and calibration approaches, and communication in integrated microsystems. Applications, including RF MEMS, optical MEMS, bioMEMS, and microfluidics. Design project using CAD and report preparation.
Prerequisite: none. II Alternate Years (3 credits) Production systems in large volume manufacturing (e.g., automotive, semiconductor, computer, etc.) are studied. Topics include quantitative methods for analysis of production systems; analytical methods for design of lean in-process and finished goods buffering; measurement-based methods for identification and elimination of production system bottlenecks; and system-theoretic properties of production lines.
Prerequisite: Math 419. II (3 credits) Introduction to the description and analysis of systems using function analytic methods. Metric spaces, normed linear spaces, Hilbert spaces, resolution spaces. Emphasis on using these concepts in systems problems.
Prerequisite: Graduate student or permission of instructor (3 credits) This course is intended to provide students with an understanding of the critical issues in energy technologies.
Prerequisite: ESENG 501 (3 credits) This required project course is intended to provide students with a relevant experience in energy systems.
Prerequisite: ME382 and ME 335 or equivalents (3 credits) Energy and power densities previously unattainable in environmentally-friendly energy technologies have been achieved through use of novel materials. Insertion of new materials into power supplies has changed the landscape of options. Design strategies for power systems are described, in the context of growing global demand for power and energy.
Prerequisite: Senior Standing. I, II (2 credits) Review of philosophies, systems, and practices utilized by world-class manufacturers to meet current manufacturing challenges, focusing on "lean production" in the automotive industry, including material flow, plant-floor quality assurance, job design, work and management practices. Students tour plants to analyze the extent and potential of the philosophies.
Prerequisite: IOE 366 (3 credits) This course provides students with the analytical and management tools necessary to solve manufacturing quality problems and implement effective quality systems. Topics include voice of the customer analysis, the Six Sigma problem solving methodology, process capability analysis, measurement system analysis, design of experiments, statistical process control, failure mode and effects analysis, quality function deployment, and reliability analysis.
Prerequisite: permission of instructor. (to be arranged) Selected topics of current interest in industrial and operations engineering.